SBD’s services are milestone based & customer driven. We have flexible service packages that we adapt to meet your research goals. All of our packages include bi-weekly progress updates:
Service package I: Crystals & Structures
- Crystallize target protein provided by client
- Determine apo-crystal and co-crystal structure
- Structure analysis, deliver results
Service package II: Protein & Co-crystal Structures
- Design construct, express, purify, and crystallize target.
- Determine co-crystal structures with one to ten ligands
- Analyze structures and present results
Service package III: High-Throughput Crystal Structures
- Construct design, large scale protein purification at SBD
- High throughput co-crystallization.
- Determine 20-30 co-crystal structures to fully support a client’s drug discovery process.
Service Package IV: Early Lead Development Partnership
- Construct design, large scale protein purification
- High throughput co-crystallization
- Determine co-crystal structures to fully support medicinal chemistry and compound optimization.
- Activity assays, cell-based assays, binding affinity measurements
- Rational drug design using comparative structure analysis and computational chemistry