Structure based Design, Inc (SBD) provides gene-to-lead integrated drug discovery services and engages in novel drug discovery partnerships. We specialize in protein production, protein structure determination, assay development, structure-based drug design (SBDD), and fragment-based drug design (FBDD) to support lead discovery and optimization. We have worked on over 80 different drug discovery projects and solved hundreds of co-crystal structures for our clients and for internal projects since our inception in 2007. We are conveniently located in San Diego and provided unparalleled scientific support. We have accelerated first-in-class drug discovery efforts using structure-based design approaches, shaving years and millions of dollars off compound development. Drug discovery programs supported by our work have resulted in more than ten clinical stage compounds for our clients.